USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O14558 USC-OGP 2-DE database:  O14558 O14558 General information about the entry View entry in simple text format Entry name HSPB6_HUMAN Primary accession number O14558 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Heat shock protein beta-6; Short=HspB6; AltName: Full=Heat shock 20 kDa-like protein p20;. Gene name Name=HSPB6 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1316: pI=6.18; Mw=19834 Cross-references UniProtKB/Swiss-Prot O14558; HSPB6_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name HSPB6_HUMAN Primary accession number O14558 Secondary accession number(s) O14551 Q6NVI3 Q96MG9 Sequence was last modified on  August 2, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 142) Name and origin of the protein Description RecName: Full=Heat shock protein beta-6; Short=HspB6; AltName: Full=Heat shock 20 kDa-like protein p20; Gene name Name=HSPB6 Encoded on Name=HSPB6 Keywords 3D-structure; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Secreted; Stress response. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AK056951; BAB71323.1; -; mRNA EMBL AC002398; AAB81196.1; -; Genomic_DNA EMBL BC068046; AAH68046.1; -; mRNA CCDS CCDS12475.1; -; . PIR B53814; B53814; . PIR T00703; T00703; . RefSeq NP_653218.1; NM_144617.2; . UniGene Hs.534538; -; . UniGene Hs.744178; -; . PDB 4JUS; X-ray; 2.50 A; A/B/C/D/E/F/G/H=57-160 PDB 4JUT; X-ray; 2.20 A; A/B/C/D/E/F/G/H=57-160 PDB 5LTW; X-ray; 4.50 A; C/D/G/H/K/L=1-149 PDB 5LU1; X-ray; 2.40 A; C/D/G/H=13-20 PDB 5LU2; X-ray; 2.50 A; C/D=11-23 PDB 5LUM; X-ray; 2.60 A; A/B/C/D/E=72-149 F/G/H/I/J=2-10 PDBsum; 4JUS; -; . PDBsum 4JUT; -; . PDBsum 5LTW; -; . PDBsum 5LU1; -; . PDBsum 5LU2; -; . PDBsum 5LUM; -; . ProteinModelPortal O14558; -; . SMR O14558; -; . BioGrid 125988; 9; . IntAct O14558; 51; . MINT MINT-7002024; -; . STRING 9606.ENSP00000004982; -; . iPTMnet O14558; -; . PhosphoSitePlus O14558; -; . BioMuta HSPB6; -; . REPRODUCTION-2DPAGE O14558; -; . UCD-2DPAGE O14558; -; . PaxDb O14558; -; . PeptideAtlas O14558; -; . PRIDE O14558; -; . Ensembl ENST00000004982; ENSP00000004982; ENSG00000004776; . Ensembl ENST00000592984; ENSP00000468057; ENSG00000004776; . GeneID 126393; -; . KEGG hsa:126393; -; . CTD 126393; -; . DisGeNET 126393; -; . GeneCards HSPB6; -; . HGNC HGNC:26511; HSPB6; . HPA CAB001974; -; . HPA HPA044153; -; . HPA HPA054811; -; . MIM 610695; gene; . neXtProt NX_O14558; -; . OpenTargets ENSG00000004776; -; . PharmGKB PA134983584; -; . eggNOG KOG3591; Eukaryota; . eggNOG ENOG410YERS; LUCA; . GeneTree ENSGT00760000119238; -; . HOGENOM HOG000233954; -; . HOVERGEN HBG054766; -; . InParanoid O14558; -; . KO K09545; -; . OMA AFAPYYL; -; . OrthoDB EOG091G0USC; -; . PhylomeDB O14558; -; . SignaLink O14558; -; . SIGNOR O14558; -; . GeneWiki HSPB6; -; . GenomeRNAi 126393; -; . PRO PR:O14558; -; . Proteomes UP000005640; Chromosome 19; . Bgee ENSG00000004776; -; . CleanEx HS_HSPB6; -; . ExpressionAtlas O14558; baseline and differential; . Genevisible O14558; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0051087; F:chaperone binding; IPI:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; ISS:UniProtKB; . GO GO:0005212; F:structural constituent of eye lens; IEA:InterPro; . GO GO:0051082; F:unfolded protein binding; IDA:UniProtKB; . GO GO:0061077; P:chaperone-mediated protein folding; IDA:UniProtKB; . GO GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IEA:Ensembl; . GO GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB; . GO GO:0006937; P:regulation of muscle contraction; IEA:Ensembl; . Gene3D 2.60.40.790; -; 1; . InterPro IPR002068; A-crystallin/Hsp20_dom; . InterPro IPR001436; Alpha-crystallin/HSP; . InterPro IPR012273; Alpha-crystallin_B; . InterPro IPR003090; Alpha-crystallin_N; . InterPro IPR031107; HSP20; . InterPro IPR008978; HSP20-like_chaperone; . PANTHER PTHR11527; PTHR11527; 1; . PANTHER PTHR11527:SF229; PTHR11527:SF229; 1; . Pfam PF00525; Crystallin; 1; . Pfam PF00011; HSP20; 1; . PRINTS PR00299; ACRYSTALLIN; . SUPFAM SSF49764; SSF49764; 1; . PROSITE PS01031; HSP20; 1; .

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